TF and HIV 1

Preliminary observations using HIV-specific transfer factor in AIDS. Biotherapy. 1996;9(1-3):41-7.

Pizza G, Chiodo F, Colangeli V, Gritti F, Raise E, Fudenberg HH, De Vinci C, Viza D
Immunodiagnosis and Immunotherapy Unit, Ospedale S. Orsola-Malpighi, Bologna, Italy.

Twenty five HIV-1-infected patients, at various stages (CDC II, III and IV) were treated orally with HIV-1-specific transfer factors for periods varying from 60 to 1870 days. All patients were receiving antiviral treatments in association with transfer factors. The number of lymphocytes, CD4 and CD8 subsets were followed and showed no statistically significant variations. In 11/25 patients the number of lymphocytes increased, whilst in 11/25 decreased; similarly an increase of the CD4 lymphocytes was observed in 11/25 patients and of the CD8 lymphocytes in 15/25. Clinical improvement or a stabilized clinical condition was noticed in 20/25 patients, whilst a deterioration was seen in 5/25. In 12/14 anergic patients, daily transfer factors administration restored delayed type hypersensitivity to recall antigens within 60 days. These preliminary observations suggest that oral HIV-specific transfer factors administration, in association with antiviral drugs, is well tolerated and seems beneficial to AIDS patients, thus warranting further investigation.

PMID: 8993756 [PubMed - indexed for MEDLINE]


Biotherapy. 1996;9(1-3):49-54.

Preliminary results in HIV-1-infected patients treated with transfer factors (TF) and zidovudine (ZDV).
Dept. of Infectious Diseases, Maggiore Hospital, Bologna, Italy.

The efficiency of HIV-1 specific transfer factors administration, combined with Zidovudine (ZDV), in asymptomatic persistent generalised lymphadenopaty, or AIDS related complex (ARC) patients was evaluated. Twenty patients were randomly assigned to receive only ZDV (1st group) or ZDV together with HIV-1-specific TF (2nd group). HIV-1-specific TF was administered orally at 2 x 10(7) cell equivalent daily for 15 days, and thereafter once a week for up to 6 months. There were no significant differences between the two groups in clinical evolution, red blood cells, haemoglobin, lymphocytes, CD20 subset, transaminases, beta-2-microglobulin, p24 antigen. White blood cells, CD8 lymphocytes as well as IL-2 levels increased in the second group, while the CD4 subset increased in the first group. The combination treatment with ZDV and transfer factors appeared to be safe and well tolerated. Furthermore, levels of serum cytokines were investigated in 10 patients (8 asymptomatic and 2 ARC) treated with ZDV, and compared with 5 patients of the 2nd group (3 asymptomatic and 2 ARC) treated with ZDV plus HIV-1-specific transfer factors. Peripheral lymphocytes, CD4, CD8 subsets, IL-2, TNF alpha, IL-6, p24 antigen, IL-2 soluble lymphocyte receptors (sR), CD4sR, CD8sR and beta-2-microglobulin were evaluated at the baseline and at the 3rd month. The CD4 subset was not significantly different in the two groups, whilst IL-2 increased in the 2nd group receiving ZDV plus transfer factors, suggesting an activation of the Th1 secretion pattern.
PMID: 8993757 [PubMed - indexed for MEDLINE]

Sb Ved Pr Lek Fak Karlovy Univerzity Hradci Kralove. 1993;36(3):117-37.

Biochem Biophys Res Commun. 2004 Dec 17;325(3):1075-81.
Non-induced leukocyte extract reduces HIV replication and TNF secretion.
Department of Cell Biology, Center for Genetic Engineering and Biotechnology, Ave. 31 e/ 158 y 190, Cubanacán, Playa, AP: 6162, Havana 10600, Cuba. celia.fernandez@cigb.edu.cu

According to UNAIDS, the global HIV/AIDS epidemic increased to 40 million the number of people living with the virus around the world. Dialyzable leukocyte extract obtained by our group is a low molecular weight dialyzable material from peripheral human leukocytes previously in vitro induced with Sendai virus (DLE-ind), and more recently, from non-induced leukocytes (DLE n/i). Previous results have shown the ability of DLE-ind to inhibit HIV in vitro replication in MT4 cell; to reduce TNFalpha secretion, and to delay in vivo progression to AIDS in early stage of HIV infection. In this work we present evidences that DLE n/i also inhibits HIV in vitro replication and reduces TNFalpha secretion in human whole blood like DLE obtained from induced leukocytes. Taking together these results show that both properties of DLE, HIV in vitro inhibition and TNF production modulation, are not dependent on in vitro Sendai virus induction of leukocytes.
PMID: 15541398 [PubMed - indexed for MEDLINE]

7 comments:


  1. So is possible that HIV Disease can be cured because i have been scammed so many times not until i came across this great man dr akhigbe who helped me at first I never believe all this comment and post about him and I was very sick because i have been infected with HIV Disease for the past two year,just last 2months I keep reading the testimony about this man named dr akhigbe they said that the man is so powerful he have cured different type of diseases, I keep monitor the post of some people about this man and I found out that he was real so i decided to give him a trial I contacted him for help and he said he was going to help me get my cure that all i needed to do was to send him money to prepare the medication after which it will be sent to me via dhl service which i did to my greatest surprise the medication was sent to me he gave me instructions on how to use it that after three weeks i should go for check up,after taking the medicine and follow his instruction after three weeks i went back to the hospital for another test, at first i was shocked when the doctor told me that i was negative i ask the doctor to check again and the result was still the same negative that i was now free from HIV Disease at of the shock i decided to come and share my own testimony with you for those who think there is no cure for HIV Disease the cure as finally come' stop doubting and contact dr akhigbe via email drrealakhigbe@gmail.com he will help you out you can also wattssap him via +2348142454860 he is also perfect in curing DIABETICS,HERPES,HIV/AIDS, INFERTILITY;ALS,ANCE PIMPUS,LUPUS VIRUS ,SYPHILLIS, PENIS AND BREAST ENLARGEMENT, LOW SPERM COUNT, MENINGITIES AND HEPATITIES B[HBV] DISEASES, believe me that deadly disease is not longer a deadly sentence becauase dr akhigbe has the cure.

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  2. LEONA KNIGHT
    Am leona knight
    Thanks to God and also to dr akhigbe , the great herbal man that cured me of HERPES. I contacted the virus from my partner 4 year ago, i almost spent all i had because i was restless , until i saw peoples testimony about Dr akhigbe recommendation online for how he has being curing HERPES with his herbs herbal medicine , and i emailed him and tell him my problem and he prepare my cure and send it to me through UPS and gave me instructions on how to use the herbs herbal medicine, i followed as i was instructed for 2weeks and behold after i finish drinking it i notice something in me, i went to the hospital for checkup and the result was negative and the virus was completely gone from my body. You can contact Dr akhigbe to get your herbs too and cure yourself from these virus. You can email him on drrealakhigbe@gmail.com or you call him and whatsapp him on +2348142454860. . Dr akhibge cure so many different type of diseases with his herbal herbs such as HERPES, HIV/AIDS. CANCER of all kind, DIABETES and so many more. I want to thank God for using Dr akhibge to cure me. He is real.

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  3. Brothers and sister, let me use these opportunity to introduce a great doctor that cured ME FROM HIV/AIDS WITH HIS HERBAL MEDICINE. Dr Akhigbe, he is also know as the godfather of berbalism and all kind of root to cure different diseases.i meant his different testimonies on this blog site i also reach him through his email. first he encourage me with good advise, he told me to stop thinking on about the HIV and let my mind be free.secoundly he learnt me a short lesson that was very cleard to me and make me to understand that using condom when having sex is best protction. how ever,
    The period of HIV infection to develop in the body is about three to four weeks. This period can, however, be longer up to 3 months and in rare cases up to 6 months. Most people generally develop detectable HIV antibodies by current method within 3 months of infection or to 6 months before it expand to years.Dr Akhigbe feel for patienas as his own sons and daughters he sent my herbal medicine through UPS express delivery and it took me 5 working days before i received it, he also instruction me on on how to use it. he is a good caring doctor he must write me each day to know if am following up with the herbal merdicine for good three weeks before he later order me to go to hoapitle for another test and i get a surprise result, that was how i get my freedom from the hand of hiv/aids.Dr Akhigbe also use his herbal medicine to cure diseases like HERPES ,HIV/AIDS , DIABETES , CANCER , ALS etc for his help please reach him through his email drrealakhigbe@gmail.com or whatapp him +2348142454860

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  4. It is no secret that I have a very deep and personal relationship with God. I have pushed and resisted that relationship this past year through all the bullshit I have had to go through living with Herpes but once again, God is bigger than my stubbornness and broke through that outbreak cold sore and all I had Genital Herpes. For me personally, hearing over and over how I am not good enough has really invaded my mind in the worst way possible. I completely shut down and I was just waking up like is this how life going to end this temporary herpes outbreak “fuck everybody with herpes if you know what I mean” but let's be honest here...It is a cowardly to say no to herbal medicine. It is fear based. And it is dishonest to what my heart wants. Don't build a wall around yourself because you are afraid of herbals made or taking a bold step especially when it's come to health issues and getting cure. So many young men/ women tell me over and over that Dr Itua is going to scam me but I give him a try to today I feel like no one will ever convince me about herbal medicine I accept Dr Itua herbal medicine because it's cure my herpes just two weeks of drinking it and i have been living for a year and months now I experience outbreak no more, You can contact him if you need his herbal medicine for any such diseases like, Herpes, Hepatitis, HIV, Epilepsy, Infertility, Love Spell,. Email..drituaherbalcenter@gmail.com then what's app.+2348149277967.... My advice to any sick men/women out there is simple... Be Always an open book. Be gut wrenching honest about yourself, your situation, and what you are all about. Don't hold anything back. Holding back will get you nowhere...maybe a one way ticket to lonelyville and that is NOT somewhere you want to be. So my final truth...and I'm just starting to grasp this one..

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  5. But Dr. Itua, Traditional Herbal Practitioner in Africa, Have cured for HIV which is extracted from some rare herbals. It is highly potential to cure AIDS 100% without any residue. Dr Itua herbal medicine has already passed various blogs on how he use his powerful herbals to heal all kind of diseases such as. Herpes, HIV, Diabetes, Hepatitis, Epilepsy, also his herbal boost immune system as well. I'm telling this because he uses his herbal medicine to cure me from hepatitis B and HIV, which i have being living for 9 months now with no side effect. The Herbal Medicine is just as good when drinking it although i have to use rest room after drinking it which I do not really care about because i just want to get the virus out of my body, I will recommend Dr Itua to anyone sick out here to contact Dr Itua with this following information.
    Email...drituaherbalcenter@gmail.com
    Whatsapp Or Call...+2348149277967.
    He might be late to respond because he always busy with patent, but he will surely get back to you with positive response.

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  6. Hello everyone, I want use this opportunity share some thought about GENITAL HERPES in case you have someone suffering from it, my thought on this, is that you can get some herbs that can cure this disease, I have seen it work and I'm confident to recommend it to you today and to get the herbs for GENITAL HERPES contact Dr Ekpen via: (ekpentemple@gmail.com) or via whatsapp +2347050270218

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  7. Here is  my testimony on how I was cured of HIV by Dr Akhigbe,with his natural herbal medicine.  on a regular basis in efforts to help others when I could. As you may know, each donation is tested.  Well, on July 6th I had a meeting with a Red Cross representative and was told that I had HIV. “What went through your mind when you heard that "Rose" Good question reader! To be honest, I thought my life was over, that I would ever find love, get married, have children or anything normal. Lucky for me I have an amazing support system.  My family supported me then I never thought that I was invincible to STD s or pregnancy or anything else parents warn their kids about. I just didn’t think about it. I was in a monogamous relationship and thought that I asked the right questions.  We even talked about marriage Scary.  During that time I was in college and donated blood on a re as well. who helped me in search of cure through the media.there we saw a good testimony of sister 'Kate' about the good work of Dr Akhigbe natural herbal medicine cure.then I copied his email address and contacted him. A good herbalist doctor with a good heart, he is kind, loving and caring. He replied back to my message and told me what to do. After a week the doctor sent me my herbal medicine and instructed me how to take it.Yes it worked very well, after drinking it I went to the hospital for another test and everything turned negative. What a wonderful testimony I can never forget in my life. Dr Akhigbe is a man who gave me a life to live happily forever so all I want you all to believe and know that cure of HIV is real and herbs is a powerful medicine and it works and heals.  Dr Akhigbe also used his herbal medicine to cure diseases like:   HERPES, DIABETES, SCABIES, HEPATITIS A/B, STROKE, CANCER, ALS, TUBERCULOSIS, ASTHMA, PENIS ENLARGEMENT, MALARIA, LUPUS, LIVER CIRRHOSIS, DEPRESSION, HIV/AIDS, EPILEPSY, BACTERIAL, DIARRHEA, HEART DISEASES, HIGH BLOOD PRESSURE, PARKINSON'S, ALZHEIMER, COLD URTICARIA, HUMAN PAPILLOMAVIRUS,INSOMNIA,  BACTERIAL VAGINOSIS, SCHIZOPHRENIA, JOINT PAIN, STOMACH PAIN, CHROME DISEASES, CHLAMYDIA, INSOMNIA HEARTBURN, ,  THYROID, MAR BURG DISEASES, MENINGITIS, ARTHRITIS, BODY WEAK, SMALLPOX, DENGUE, FEVER, CURBS, CHANCRE, AND OTHERS VARIOUS DISEASES/ VIRUS.   You are there and you find yourself in any of these situations, kindly contact Dr Akhigbe now to help you get rid of it. Here is his email address:
       drrealakhigbe@gmail.com      or you can write to him on whats app with his phone number:   +2349010754824.
      My appreciation is to share his testimony for the world to know the good work Dr Akhigbe has done for me and he will do the same for you.
       

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